PHT-LEU-OH

Base Information

High Quality Chinese Factory supply 2419-38-7 PHT-LEU-OH

  • Molecular Formula: C14H15NO4
  • Molecular Weight: 261.277
  • Vapor Pressure: 4.95E-08mmHg at 25°C 
  • Boiling Point: 426.4 °C at 760 mmHg 
  • Flash Point: 211.7 °C 
  • PSA: 74.68000 
  • Density: 1.311 g/cm3 
  • LogP: 1.71980 

PHT-LEU-OH(Cas 2419-38-7) Usage

InChI:InChI=1/C14H15NO4/c1-8(2)7-11(14(18)19)15-12(16)9-5-3-4-6-10(9)13(15)17/h3-6,8,11H,7H2,1-2H3,(H,18,19)/p-1/t11-/m1/s1

2419-38-7 Relevant articles

Absolute configuration of α-phthalimido carboxylic acid derivatives from circular dichroism spectra

Skowronek,Gawronski

, p. 4585 - 4590 (1999)

It is demonstrated that the Cotton effec...

Enantiomerically Pure [2.2]Paracyclophane-4-thiol: A Planar Chiral Sulfur-Based Building Block Readily Available by Resolution with an Amino Acid Chiral Auxiliary

Vincent, Adrien,Deschamps, Damien,Martzel, Thomas,Lohier, Jean-Fran?ois,Richards, Christopher J.,Gaumont, Annie-Claude,Perrio, Stéphane

, p. 3961 - 3966 (2016)

Acyl chloride of N-phthaloyl-(S)-isoleuc...

Stereocontrolled synthesis of (S)-γ-fluoroleucine

Padmakshan, Dharshana,Bennett, Simon A.,Otting, Gottfried,Easton, Christopher J.

, p. 1083 - 1084 (2007)

Starting with (S)-leucine, the correspon...

Chiral sensors for determining the absolute configurations of α-amino acid derivatives

Chen, Zhongxiang,Fan, Hongjun,Yang, Shiwei,Bian, Guangling,Song, Ling

, p. 6933 - 6939 (2018)

A simple strategy for configurational as...

Structure-Activity Relationships for the Marine Natural Product Sintokamides: Androgen Receptor N-Terminus Antagonists of Interest for Treatment of Metastatic Castration-Resistant Prostate Cancer

Yan, Luping,Banuelos, Carmen A.,Mawji, Nasrin R.,Patrick, Brian O.,Sadar, Marianne D.,Andersen, Raymond J.

, p. 797 - 813 (2020/11/13)

Synthetic analogues of the marine natura...

Photoinduced and Palladium-Catalyzed Remote Desaturation of Amide Derivatives

Jin, Weiwei,Yu, Shouyun

supporting information, p. 6931 - 6935 (2021/09/11)

A photoinduced and palladium-catalyzed r...

DUAL KINASE-BROMODOMAIN INHIBITORS

-

Page/Page column 92; 123; 124, (2021/12/12)

Provided herein are compounds of Formula...

A base-controlled switch of SO2 reincorporation in photocatalyzed radical difunctionalization of alkenes

Bellotti, Peter,Glorius, Frank,Paulisch, Tiffany O.,Wang, Huamin,Zhang, Xiaolong

supporting information, p. 3412 - 3424 (2021/12/14)

Control of selectivity is a pivotal chal...

2419-38-7 Process route

N-(o-carboxybenzoyl)-L-leucine
6707-69-3

N-(o-carboxybenzoyl)-L-leucine

L-leucine
61-90-5,21675-61-6,25248-98-0,70-45-1

L-leucine

benzene-1,2-dicarboxylic acid
88-99-3,73607-73-5

benzene-1,2-dicarboxylic acid

N-phthaloyl-(S)-leucine
2419-38-7

N-phthaloyl-(S)-leucine

Conditions
Conditions Yield
With hydrogenchloride; potassium chloride; In acetonitrile; at 50 ℃; pH=1.00; Further Variations:; pH-values; Kinetics; Product distribution;
L-leucine
61-90-5,21675-61-6,25248-98-0,70-45-1

L-leucine

N-ethoxycarbonylphthalimide
22509-74-6

N-ethoxycarbonylphthalimide

N-phthaloyl-(S)-leucine
2419-38-7

N-phthaloyl-(S)-leucine

Conditions
Conditions Yield
With sodium carbonate; In water; at 20 ℃; for 2h;
100%
With sodium carbonate; In water; at 20 ℃; for 2h;
100%
With sodium hydrogencarbonate; In water; for 1h; Ambient temperature;
66%
With sodium carbonate; In water;
35%
With sodium carbonate; In water; at 20 ℃; for 5h;
With sodium carbonate; In water; at 20 ℃; for 3h;

2419-38-7 Upstream products

  • 85-44-9
    85-44-9

    phthalic anhydride

  • 61-90-5
    61-90-5

    L-leucine

  • 5115-64-0
    5115-64-0

    N -(1-carboxy-3-methyl-butyl)-phthalamic acid

  • 22509-74-6
    22509-74-6

    N-ethoxycarbonylphthalimide

2419-38-7 Downstream products

  • 30816-20-7
    30816-20-7

    N ,N -phthaloyl-L-leucine anilide

  • 342392-03-4
    342392-03-4

    N ,N -phthaloyl-L-leucine-[2]naphthylamide

  • 19506-89-9
    19506-89-9

    N-phthaloyl-DL-leucine

  • 99036-46-1
    99036-46-1

    N ,N -phthaloyl-L-leucine-(4-nitro-phenyl ester)

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