What is the Heptafluorobutyric acid?

Heptafluorobutyric acid is Clear colorless to faintly yellow liquid, while it's Molecular Formula is C4HF7O2. Clear colorless to faintly yellow liquid Perfluorobutyric acid was used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It was used as ion pairing reagent in preparative and analytical reserved phase HPLC of underivatised peptides.

What is the CAS number for Heptafluorobutyric acid?

The CAS number of Heptafluorobutyric acid is 375-22-4.

What is Heptafluorobutyric acid (375-22-4) used for?

Heptafluorobutyric acid (HBFA) is a strong acid and ion-pairing agent that is perfluorinated butyric acid. It is a clear colorless to faintly yellow liquid, known for its excellent resolution in various applications. HBFA is widely used in analytical chemistry, particularly in high-performance liquid chromatography (HPLC) and gas chromatography/mass spectrometry (GC/MS), due to its strong acidity and hydrophobic nature.InChI:InChI=1/C4HF7O2/c5-2(6,1(12)13)3(7,8)4(9,10)11/h(H,12,13)/p-1

What is the Heptafluorobutyric acid?

Heptafluorobutyric acid is Clear colorless to faintly yellow liquid, while it's Molecular Formula is C4HF7O2. Clear colorless to faintly yellow liquid Perfluorobutyric acid was used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It was used as ion pairing reagent in preparative and analytical reserved phase HPLC of underivatised peptides.

What is the CAS number for Heptafluorobutyric acid?

The CAS number of Heptafluorobutyric acid is 375-22-4.

What is Heptafluorobutyric acid (375-22-4) used for?

Heptafluorobutyric acid (HBFA) is a strong acid and ion-pairing agent that is perfluorinated butyric acid. It is a clear colorless to faintly yellow liquid, known for its excellent resolution in various applications. HBFA is widely used in analytical chemistry, particularly in high-performance liquid chromatography (HPLC) and gas chromatography/mass spectrometry (GC/MS), due to its strong acidity and hydrophobic nature.InChI:InChI=1/C4HF7O2/c5-2(6,1(12)13)3(7,8)4(9,10)11/h(H,12,13)/p-1

Heptafluorobutyric acid

Base Information

Chemical Name: Heptafluorobutyric acid
CAS No.: 375-22-4

Top Quality Chinese Manufacturer supply 375-22-4 Heptafluorobutyric acid

Molecular Formula: C4HF7O2
Molecular Weight: 214.04
Appearance/Colour: Clear colorless to faintly yellow liquid
Vapor Pressure: ~10 mm Hg ( 25 °C)
Melting Point: -17.5 °C
Refractive Index: n20/D 1.3(lit.)
Boiling Point: 120.2 °C at 760 mmHg
PKA: pK1:0.17 (25°C)
Flash Point: 18 °C
PSA： 37.30000
Density: 1.679 g/cm³
LogP: 1.90390

Heptafluorobutyric acid(Cas 375-22-4) Usage

Purification Methods	Fractionally distil the acid twice in an Oldershaw column (p 10) with an automatic vapour-dividing head, the first distillation being in the presence of conc H2SO4 as a drying agent. (Take care with the hot acid.) [Beilstein 2 IV 810.]
Definition	ChEBI: A monocarboxylic acid that is perfluorinated butyric acid.
General Description	Perfluorobutyric acid is an effective additive for zinc electrodeposition.

InChI:InChI=1/C4HF7O2/c5-2(6,1(12)13)3(7,8)4(9,10)11/h(H,12,13)/p-1

375-22-4 Relevant articles

Dibutyltin perfluoroalkanecarboxylates: Synthesis, NMR characterization and in vitro antitumour activity

Kemmer, Martine,Dalil, Hassan,Biesemans, Monique,Martins, José C.,Mahieu, Bernard,Horn, Ernst,De Vos, Dick,Tiekink, Edward R. T.,Willem, Rudolph,Gielen, Marcel

, p. 63 - 70 (2000)

Three dibutyltin perfluoroalkanecarboxyl...

-

Nagase,Kojima

, p. 1468,1470 (1961)

REACTIVITY OF ELECTROCHEMICALLY GENERATED SUPEROXIDE ANION WITH F-BUTYL IODIDE. SYNTHESIS OF PERFLUORO BUTANOIC ACID

Dapremont-Avignon, C.,Calas, P.,Amatore, C.,Commeyras, A.

, p. 219 (1991)

Aerobic biotransformation studies of two trifluoromethoxy-substituted aliphatic alcohols and a novel fluorinated C3-based building block

Fr?mel, Tobias,Knepper, Thomas P.

, p. 80 - 89 (2015)

Fluorinated substances play a significan...

Electrocatalytic degradation of perfluorooctanoic acid by LaNixY1-xO3 (Y = Fe, Cu, Co, Sr) gas dispersion electrode

Chen, Yongyang,Guo, Dan,Dong, Xiaochun,Li, Yahui,Huang, Yixuan,Chen, Hao,Li, Shanping

, (2020/12/23)

Perfluorooctanoic acid (PFOA), as a refr...

Oxidation of fluoroalkyl alcohols using sodium hypochlorite pentahydrate [1]

Kirihara, Masayuki,Suzuki, Katsuya,Nakakura, Kana,Saito, Katsuya,Nakamura, Riho,Tujimoto, Kazuki,Sakamoto, Yugo,Kikkawa, You,Shimazu, Hideo,Kimura, Yoshikazu

, (2021/02/05)

Fluoroalkyl alcohols are effectivity oxi...

Heptafluorobutyric acid and preparation method of derivative thereof

-

Paragraph 0102; 0105-0107, (2017/07/18)

The invention provides a preparation met...

The effect of oxygen in the photocatalytic oxidation pathways of perfluorooctanoic acid

Sansotera, Maurizio,Persico, Federico,Rizzi, Valentina,Panzeri, Walter,Pirola, Carlo,Bianchi, Claudia L.,Mele, Andrea,Navarrini, Walter

, p. 159 - 168 (2015/11/10)

The influence of oxygen in the photocata...

375-22-4 Process route

: 3869-06-5
heptafluoro-butyric acid-(4-nitro-anilide)

: 375-22-4
heptafluorobutyric Acid

: 100-01-6,104810-17-5
4-nitro-aniline

Conditions

Conditions	Yield
With buffer CO₃^2-; water; hydrogen carbonate; sodium chloride; In acetonitrile; at 25 ℃; Rate constant; also in the presence of β-cyclodextrin, other buffer;