4-Chlorothiophenol
Base Information
- Chemical Name: 4-Chlorothiophenol
- CAS No.: 106-54-7
Top Quality Chinese Factory supply 106-54-7 4-Chlorothiophenol
- Molecular Formula: C6H5ClS
- Molecular Weight: 144.625
- Appearance/Colour: white to almost white crystalline solid
- Vapor Pressure: 0.335mmHg at 25°C
- Melting Point: 49-51 °C
- Refractive Index: 1.5480
- Boiling Point: 206.8 °C at 760 mmHg
- PKA: pK1:5.9 (25°C)
- Flash Point: 78.6 °C
- PSA: 38.80000
- Density: 1.268 g/cm3
- LogP: 2.62870
4-Chlorothiophenol(Cas 106-54-7) Usage
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Synthesis Reference(s) |
The Journal of Organic Chemistry, 27, p. 4455, 1962 DOI: 10.1021/jo01059a081Synthetic Communications, 18, p. 575, 1988 DOI: 10.1080/00397918808064014 |
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Hazard |
Toxic by ingestion. |
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Purification Methods |
Recrystallise the thiophenol from aqueous EtOH. The SMe ether has m 129o and the SEt ether has m 64o. [D'Sousa et al. J Org Chem 52 1720 1987, Beilstein 6 H 326, 6 I 149, 6 III 1034.] |
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General Description |
4-Chlorothiophenol undergoes oxidative coupling catalyzed by iron(III)-tetra phenyl prophyrin to form disulfides. |
InChI:InChI=1/C6H5ClS/c7-5-1-3-6(8)4-2-5/h1-4,8H/p-1
106-54-7 Relevant articles
-
Oae,Tsuchida
, p. 1283 (1972)
-
Specific features of reaction between 1,2-dinitro-and 1-nitro-2-thioethenes and hydrazine
Kretser,Kuz'mina,Lipina,Berkova,Berestovitskaya
, p. 1202 - 1203 (2003)
-
-
Fedor,Murty
, p. 8410,8411 (1973)
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Oxidative Cyclization of 4-(2-Mercaptophenyl)-Substituted 4H-1,2,4-Triazolium Species to Tricyclic Benzothiazolium Salts
Ardón-Mu?oz, Luis G.,Bolliger, Jeanne L.
, (2022/04/12)
Herein we report a generally applicable ...
Novel synthesis method of chlorolucanthone
-
Paragraph 0029; 0031; 0034; 0036; 0039; 0041; 0044; 0046, (2020/10/21)
The invention discloses a novel synthesi...
High-performance sono/nano-catalytic system: Fe3O4?Pd/CaCO3-DTT core/shell nanostructures, a suitable alternative for traditional reducing agents for antibodies
Taheri-Ledari, Reza,Maleki, Ali,Zolfaghari, Ehsan,Radmanesh, Maral,Rabbani, Hodjattallah,Salimi, Ali,Fazel, Ramin
, (2019/11/02)
Herein, a novel heterogeneous nanoscale ...
Novel synthesis method for thiophenol derivative
-
Paragraph 0018; 0035-0037, (2019/04/30)
The invention discloses a novel synthesi...
106-54-7 Process route
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2127-03-9
2,2'-dipyridyldisulphide
-
-
98-66-8
4-chloro-benzenesulfonic acid
-
-
603-35-0
triphenylphosphine
-
-
2637-34-5,73018-10-7
2-Sulfanylpyridine
-
-
106-54-7
p-Chlorothiophenol
-
-
791-28-6
Triphenylphosphine oxide
| Conditions | Yield |
|---|---|
|
In
benzene;
for 4h;
Product distribution;
Mechanism;
Heating;
further reaction partners - various diaryl disulfides;
|
53%
65% |
-
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24252-90-2
S-(p-nitrophenyl) p-chlorothiobenzoate
-
-
62-53-3
aniline
-
-
6833-15-4
4-chlorobenzanilide
-
-
619-50-1
4-nitrobenzoic acid methyl ester
-
-
3460-11-5
4-nitrobenzanilide
-
-
106-54-7
p-Chlorothiophenol
| Conditions | Yield |
|---|---|
|
In
methanol;
at 55 ℃;
for 72h;
Rate constant;
k2=60.2E-4 dm3mol-1S-1;
|
106-54-7 Upstream products
-
20114-14-1
(4-chloro-phenyl)-(2,4-dinitro-phenyl)-sulfide
-
15151-78-7
ethyl S-(4-chlorophenyl) thiolcarbonate
-
873-77-8
(4-chlorphenyl)magnesium bromide
-
98-60-2
4-chlorobenzenesulfonyl chloride
106-54-7 Downstream products
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36155-35-8
2-[(4-chlorophenyl)sulfanyl]ethanamine
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6631-77-2
<4-chlor-phenyl> -piperidinomethyl-sulfid 4-chlor-phenyl>
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93483-85-3
(4-chloro-phenylsulfanyl)-succinic acid
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6310-30-1
S-(4-chlorophenyl) furan-2-carbothioate
Product recommendations
- Isobutyl Decanoate
- 2-Allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one
- N,N-DIMETHYL-1-PHENYLETHYLAMINE
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- H-ASU-OH
- TRIACONTYLDIMETHYLCHLOROSILANE
- 3-HYDROXYPICOLINAMIDE
- 1-Ethylimidazolidine-2,4-dione