1-methyl-2-phenylpiperidine

Base Information

  • Chemical Name: 1-methyl-2-phenylpiperidine
  • CAS No.: 36939-28-3

Factory Sells Best Quality 1-methyl-2-phenylpiperidine 36939-28-3 with ISO standards

  • Molecular Formula: C12H17 N
  • Molecular Weight: 175.274
  • Vapor Pressure: 0.0263mmHg at 25°C 
  • Boiling Point: 247°Cat760mmHg 
  • Flash Point: 94.2°C 
  • PSA： 3.24000 
  • Density: 0.964g/cm3 
  • LogP: 2.78130 

1-methyl-2-phenylpiperidine(Cas 36939-28-3) Usage

General Description

1-methyl-2-phenylpiperidine, also known as MPPP, is a chemical compound that belongs to the class of piperidine derivatives. It is a psychoactive central nervous system stimulant and is also known as a designer drug. MPPP is synthesized from a precursor chemical called 1-methyl-4-phenyl-4-propionoxypiperidine (MPTP), which is converted into MPPP through a chemical reaction. MPPP has been found to have stimulant and hallucinogenic effects, and has been abused for its psychoactive properties. However, it is also known to have serious side effects, including neurotoxicity and potential for addiction. Due to its potency and adverse effects, MPPP is now a controlled substance in many countries, and its use is restricted for medical and research purposes only.

InChI:InChI=1/C12H17N/c1-13-10-6-5-9-12(13)11-7-3-2-4-8-11/h2-4,7-8,12H,5-6,9-10H2,1H3

36939-28-3 Relevant articles

Catalytic methylation of C-H bonds using CO2 and H2

Li, Yuehui,Yan, Tao,Junge, Kathrin,Beller, Matthias

supporting information, p. 10476 - 10480 (2016/02/18)

Formation of C-C bonds from CO2 is a muc...

A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines

Dunsmore, Colin J.,Carr, Reuben,Fleming, Toni,Turner, Nicholas J.

, p. 2224 - 2225 (2007/10/03)

Deracemization of racemic chiral tertiar...

Photophysical and photochemical behavior of intramolecular-styrene-amine exciplexes

Lewis, Frederick D.,Dasharatha Reddy,Schneider, Siegfried,Ga, Michael

, p. 3498 - 3506 (2007/10/02)

The photophysical and photochemical beha...

INTRAMOLECULAR PHOTOCHEMICAL REACTIONS OF N-ALKYL-5-PHENYL-4-PENTEN-1-AMINES

Lewis, Frederick D.,Reddy, G. Dasharatha

, p. 5293 - 5296 (2007/10/02)

Irradiation of N-alkyl-5-phenyl-4-penten...

36939-28-3 Process route

formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

2-phenylpiperidine
3466-80-6

2-phenylpiperidine

N-methyl-2-phenylpiperidine
36939-28-3

N-methyl-2-phenylpiperidine

Conditions
Conditions Yield
With formic acid; at 150 ℃; for 0.0833333h; microwave irradiation;
41%
(E)-5-Phenyl-pent-4-enoic acid methylamide
131529-91-4

(E)-5-Phenyl-pent-4-enoic acid methylamide

N-methyl-2-phenylpiperidine
36939-28-3

N-methyl-2-phenylpiperidine

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 95 percent / lithium aluminum hydride (LAH)
2: 57 percent Chromat. / acetonitrile / Irradiation
With lithium aluminium tetrahydride; In acetonitrile;
Multi-step reaction with 3 steps
1: 95 percent / lithium aluminum hydride (LAH)
2: Michler's ketone / acetonitrile / Irradiation
3: 62 percent Chromat. / acetonitrile / Irradiation
With lithium aluminium tetrahydride; bis(p-dimethylaminophenyl)methanone; In acetonitrile;
Multi-step reaction with 2 steps
1: LiAlH4
2: Irradiation; also with N-deuterated amine (cis or trans); other N-alkyl amines
With lithium aluminium tetrahydride;

36939-28-3 Upstream products

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36939-28-3 Downstream products

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    122333-70-4

    cis-N-Methyl-5-phenyl-4-penten-1-amine

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